Il corso è tenuto in lingua Inglese. Per il contenuto si veda la seconda diapositiva del primo file pdf (FR1.pdf) seguente.
Argomenti del Corso:
- Introduction (FR1)
- Current Status of Radicals
- Chemistry What is a Radical
- Free Radicals and Life
- Historical Aspects (FR2)
- Electronic Structure and Bonding (FR3)
- Active Oxygen Specie (FR4)
- O2, O2•-·, HO2•, 1O2, H2O2, HO•
- Chemistry
- H2O2 and peroxides
- Radical Reactions
- Thermodynamics (FR6)
- Free Radical Kinetics (FR7)
- First-order FR Reaction
- Second-order FR Reaction
- Steady state approximation
- Free-radical chain reactions
- Redox chain reactions
- Inhibition in radical reactions
- Radiation Chemistry (FR8)
- Tools
- Species: e–aq, H•, HO•, H2O2, H2, O2•−
- Pulse Radiolysis/Flash Photolysis
- Lipid Peroxidation (FR9)
- Chemistry
- Analytical tools
- Effects
- Antioxidants (FR10)
- Preventive
- Chain-breaking
- Small molecules (Vit C/E, CoQ, Urate).
- Enzymes
- Chelates
- Iron and Free Radical Chemistry (FR11)
- Iron Catalyzed Reactions
- Chelates
- DNA and Protein (As radical targets) (FR12)
- Photochemical radical reactions (FR13)
- Photochemistry
- Photosensitization
- Detection of Radicals (FR14)
- TBARS
- Fluorescence
- Cyt C /NBT
- Chemiluminescence
- EPR Detection of Radicals (FR15)
- Direct Detection
- Spin Trapping
- Transition metal
- Nitric Oxide/NOS (FR16)
- Oxygen radicals/ROS (FR17)